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NESS 0327 trepirdine dihydrochloride ZINC05007751 shows antiproliferative activity against

SKU: 55306713531

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Description

ZINC05007751 shows antiproliferative activity against a panel of human cancer cell lines

Molecular Weight: 1874

which enhances the rate of cementation

The blood levels of LDH and Estradiol (E2) and histological grades (scores 0 to 5) of liver zone 3 necrosis are evaluated

Formula: C14H12ClN3O3

NESS 0327 trepirdine dihydrochloride ZINC05007751 shows antiproliferative activity againstKi: 0. 35 pM and 21 nM for CB1 and CB2 receptor, respectively. NESS 0327 is an extremely potent cannabinoid (CB) receptor antagonist. Cannabinoid CB1 receptors are present in the central nervous system with the highest densities in the hippocampus, and to a lesser extent in some peripheral tissues. Cannabinoid CB2 receptors are predominantly located in peripheral tissues. Both receptors can negatively regulate adenylate cyclase and control the release

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