Elesclomol AY-600 both β-catenin and panRas protein

both β-catenin and panRas protein levels are similarly reduced in a dose-dependent manner after treatment with KY1220

20263-07-4

SCH442416 (0

Formula: C29H30F6N4O

Yamashita Y

Elesclomol AY-600 both β-catenin and panRas proteinElesclomol, also known as STA 4783, is a HSP 90 Inhibitor, and is a small molecule bis(thio hydrazide amide) with oxidative stress induction, pro apoptotic, and potential antineoplastic activities. Elesclomol induces oxidative stress, creating high levels of reactive oxygen species (ROS), such as hydrogen peroxide, in both cancer cells and normal cells. Because tumor cells have elevated levels of ROS compared to normal cells, the increase in oxidative