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and JMJD2E with IC50 ~6
Formula: C23H25ClFN7O
Smiles: C[C@H](NC(=O)[C@@H](O)C1=CC(F)=CC(F)=C1)C(=O)N[C@@H]1C(=O)N(C)C2=CC=CC=C2C2=CC=CC=C21
may vary elsewhere
selective and orally bioavailable GPR39 agonist with an EC50 ~0
Crenolanib - CAS# 670220-88-9 60170 and JMJD2E with IC50 ~6Crenolanib, CAS No. 670220 88 9, is a potent and selective inhibitor of PDGFR , FLT3 with Kd of 2. 1 nM 3. 2 nM, 0. 74 nM, respectively, sensitive to D842V mutation not V561D mutation, and > 100 fold more selective for PDGFR than c Kit, VEGFR 2, TIE 2, FGFR 2, EGFR, erbB2, and Src. Product information CAS Number: 670220 88 9 Molecular Weight: 443. 54 Formula: C26H29N5O2 Synonym: CP 868596 RO 002 Chemical Name: 1 (2 (5 ((3 methyloxetan 3 yl)methoxy) 1H
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