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HQNO inhibition is observed with an IC50 value of 54
Wängler C
Smiles: CO[C@@H]1C[C@@H](C[C@H]2CC[C@H](C)[C@@H](O2)[C@@H](C)C(O)=O)O[C@]2(O[C@@](C)(C[C@H]2C)[C@H]2CC[C@](C)(O2)[C@@H]2O[C@H](C[C@@H]2C)[C@H]2O[C@@](O)(CO)[C@H](C)C[C@@H]2C)[C@@H]1C
Well-tolerated doses of YKL-05-099 achieve free serum concentrations above its IC50 for SIK2 inhibition for > 16 hours and reduce phosphorylation of a known SIK substrate in vivo
43(22):6959-67
Mafenide hydrochloride Catalog No.:M16403-C HQNO inhibition is observed withMafenide hydrochloride is an effective sulfonamide type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram positive and Gram negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis. Product information CAS Number: 138 37 4 Molecular Weight: 222. 69 Formula: C7H11ClN2O2S Chemical Name: 4 (aminomethyl)benzene 1 sulfonamide hydrochloride Smiles: Cl.
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