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NCGC00167123-01
2010 Sep 15
BO-264 (500 nM
2ClH/c1-4-7-9-32-34-31(25-10-16-28(17-11-25)37-23-8-22-35(5-2)6-3)24-36(32)27-14-20-30(21-15-27)38-29-18-12-26(33)13-19-29
a patient-derived tamoxifen-resistant xenograft tumor
MS 154N Size:2mg solid NCGC00167123-01MS 154N is a negative control for MS 154. The compound exhibits high binding affinity for WT and L858R mutant EGFR (Kd values are 3 and 4. 3 nM, respectively), but does not significantly induce degradation of EGFR mutants. Product information Molecular Weight: 915. 45 Formula: C47H56ClFN8O8 Chemical Name: 3 (4 (3 ((4 ((3 chloro 4 fluorophenyl)amino) 7 methoxyquinazolin 6 yl)oxy)propyl)piperazin 1 yl) N (8 ((2 (1 methyl 2,6 dioxopiperidin 3 yl) 1,3
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