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InChiKey: LWKMQFABIRSLII-MGZLOUMQSA-N
Smiles: OC(=O)C1CN(CC2=CC(F)=C(C=C2)C2=NC3=CC(CC4=CC=CC=C4F)=CC=C3S2)C1
Desmethyl Vc-seco-DUBA consists a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA)
InChiKey: ICDMLAQPOAVWNH-YHZGQTRVSA-N
as an oleanane-type triterpene saponin
CJ-2360 Catalog No.:M33349-C InChiKey: LWKMQFABIRSLII-MGZLOUMQSA-NCJ 2360 is a potent and orally active ALK inhibitor with IC50s of 2. 2, 4. 0, 8. 8, 6. 3, and 8. 9 nM against wild type ALK and F1197M, G1269A, L1196M, and S1206Y ALK mutants, respectively. CJ 2360 displays potent inhibitory activity against two clinically reported ALK mutants (C1156Y and L1196M) and a few other kinases (LTK, MERTK, CLK1, DAPK1, and DAPK2) among the 468 kinases evaluated. Product information CAS Number: 2226742 61 4 Molecular Weight: