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InChiKey: QMNWISYXSJWHRY-YLNUDOOFSA-N
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Following three intraperitoneal administrations of 3
InChi: InChI=1S/C26H22F3N5O
IP administration of I-BET151 at 30 mg/kg once per day was shown to provide survival benefit in two distinct mouse models of murine MLL–AF9 and human MLL–AF4 leukaemia
PK68 Y-100635 (maleate salt) InChiKey: QMNWISYXSJWHRY-YLNUDOOFSA-NPK68 is a potent and selective type II inhibitor of receptor interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1 dependent necroptosis. PK68 powerfully ameliorates TNF induced systemic inflammatory response syndrome, and with great potential for use in the treatment of inflammatory disorders and cancer metastasis. Product information CAS Number: 2173556 69 7 Molecular Weight: 424. 52 Formula: C22H24N4O3S Chemical Name: