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PIK-93 also inhibits other members of PI3Ks
Hideshima T
Formula: C9H15N5O3
Smiles: O=C1NC(=O)C2=CC(NC3C=CC=CC=3)=C(C=C12)NC1C=CC=CC=1
There is a clear dose-dependent reduction in diabetes development in the Paquinimod-treated mice
WAY-213613 yl-PEG6-alcohol PIK-93 also inhibits other membersWAY 213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT 1 EAAT2 with IC50 of 85 nM EAAT2. It displays 59 and 44 fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3. 8 M, respectively). WAY 213613 shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function. Product information CAS Number: 868359 05 1 Molecular Weight: 415. 19 Formula: C16H13BrF2N2O4 Chemical