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Imatinib inhibits the SLF-dependent activation of wild-type c-kit kinase activity with a IC50 for these effects of approximately 0
making it an ideal probe to study transport processes
a significant increase of CYP1A2 and CYP3A4 activity is observed at high concentrations
Smiles: COC1=C[C@@]2(CC=C)[C@H]([C@H]3C(CC=C)=C[C@]2(OC)C(=O)C3(OC)OC)C(OC)(OC)C1=O
similar to the measured M3 biding Ki
Sulfaguanidine 2-(2-phenylethyl)-5 6 7-trihydroxy-5 6 7 8-tetrahydrochromone Imatinib inhibits the SLF-dependent activationSulfaguanidine is an orally active antimicrobial agent antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery. Product information CAS Number: 57 67 0 Molecular Weight: 214. 24 Formula: C7H10N4O2S Chemical Name: N'' (4 aminobenzenesulfonyl)guanidine Smiles: NC(N)=NS(=O)(=O)C1C=CC(N)=CC=1 InChiKey: BRBKOPJOKNSWSG UHFFFAOYSA N InChi: InChI=1S C7H10N4O2S c8 5 1 3 6(4 2 5)14(12,13)11
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