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the United States (U
4S)-3-fluoro-4-hydroxycyclohexyl]pyrazin-2-yl}-N-[(1S)-1-(3-bromo-5-fluorophenyl)-2-(methylamino)ethyl]-2-fluorobenzamide
InChi: InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12
Chemical Name: 5-[2-(3-fluorophenyl)ethyl]-5-azahexacyclo[5
NNC 079202
fluoro-Dapagliflozin argyl-PEG4-alcohol the United States (UKi: 5. 3 and 330 nM for SGLT2 and SGLT1, respectively fluoro Dapagliflozin is a selective sodium glucose cotransporter (SGLT) inhibitor. Human Na(+) D glucose cotransporter (hSGLT) inhibitors constitute the newest class of diabetes drugs, blocking up to in vivo 50% of renal glucose reabsorption. In vitro: Dapagliflozin and fluoro dapagliflozin could block glucose transport and glucose coupled currents with around 100 fold specificity for hSGLT2 over
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