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to BRPF2 with a KD of 108 nM (ITC) and to BRPF3 KD of 408 nM (ITC)
Flumatinib can inhibit the phosphorylation of c-Kit in Mo7e cell and the phosphorylation of PDGFR in Swiss3T3 cell
8(9):10355-64
Integrin alpha5beta1 is expressed on endothelial cells and plays a crucial role in endothelial cell adhesion and migration
acts as a GnRH agonist
(S)-WAY 100135 dihydrochloride thacholine chloride to BRPF2 with a KD(S) WAY 100135 dihydrochloride is a potent and selective antagonist of 5 HT1A receptor with IC50 value of 15 nM. The 5 HT1A receptor is a G protein coupled receptor for endogenous neurotransmitter serotonin (5 HT) and mediates inhibitory neurotransmission. (S) WAY 100135 dihydrochloride is a potent and selective somatodendritic and postsynaptic 5 HT1A receptors antagonist. (+ ) WAY100135 inhibited 5 HT1A receptor in the rat hippocampal with IC50 value
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