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BAY11-7082
van Bochove GG
RG2833 was used at 10 µM final concentration in vitro and cellular assays
InChi: InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H
12-dienoate
Nigericin e alcohol BAY11-7082Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K+ H+ ionophore, promoting K+ H+ exchange across mitochondrial membranes. Nigericin can be a NLRP3 activator that induces the release of IL 1 as a NALP3 dependent manner. Nigericin triggers eryptosis, an effect paralleled by ROS formation, and in part due to induction of oxidative stress. Nigericin triggers apoptosis. Product information CAS Number: 28380 24 7 Molecular
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