AKR1C3-IN-4 13633 Smiles: CC(C)(CO)C1=CC=C(C=C1)S(=O)(=O)NC1=NC(=NC(OCCO)=C1OC1=CC=CC=C1O)C1=NC=CC=N1

Smiles: CC(C)(CO)C1=CC=C(C=C1)S(=O)(=O)NC1=NC(=NC(OCCO)=C1OC1=CC=CC=C1O)C1=NC=CC=N1

but fails to block carbachol (CCh)–induced TRPC4 and OAG-induced TRPC6 currents

2-(ethylsulfanyl)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine

CAS Number: 104691-86-3

28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18

AKR1C3-IN-4 13633 Smiles: CC(C)(CO)C1=CC=C(C=C1)S(=O)(=O)NC1=NC(=NC(OCCO)=C1OC1=CC=CC=C1O)C1=NC=CC=N1AKR1C3 IN 4 is a potent and selective aldo keto reductase 1C3 (AKR1C3) inhibitor with an IC50 of 0. 56 M. AKR1C3 IN 4 has the potential for castrate resistant prostate cancer (CRPC) research. Product information CAS Number: 1284180 11 5 Molecular Weight: 281. 23 Formula: C14H10F3NO2 Chemical Name: 3 {[4 (trifluoromethyl)phenyl]amino}benzoic acid Smiles: OC(=O)C1=CC(=CC=C1)NC1C=CC(=CC=1)C(F)(F)F InChiKey: MDZIRNPRVJEHHX UHFFFAOYSA N InChi: InChI=1S