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and cellular potency GNE-049 has excellent potency in the BRET cellular assay and
2-methoxyestradiol analogue ENMD-1198 reduces breast cancer-induced osteolysis and tumor burden both in vitro and in vivo
Incensole acetate (100 μM
prinaberel either was or still is under investigation by Wyeth for the treatment of some of these conditions
van Breemen RB
Enpp-1-IN-1 1689 and cellular potency GNE-049 hasEnpp 1 IN 1 (UUN28589, MV 658) is an inhibitor of Ectonucleotide pyrophosphatase phosphodiesterase 1 (enpp 1). Product information CAS Number: 2289728 58 9 Molecular Weight: 343. 40 Formula: C17H17N3O3S Synonym: UUN 28589 MV 658 Chemical Name: N {[4 (7 methoxyquinolin 4 yl)phenyl]methyl}aminosulfonamide Smiles: COC1=CC2=NC=CC(=C2C=C1)C1C=CC(CNS(N)(=O)=O)=CC=1 InChiKey: UEJMNZDIQDULLP UHFFFAOYSA N InChi: InChI=1S C17H17N3O3S c1 23 14 6 7 16 15(8 9 19