Pay in 4 interest-free payments of $7.25 Learn more
Ships within 48 hours · Estimated delivery Aug 3 - Aug 8
Formula: C17H18N6
2S)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(3-metho xyphenyl)-2-propanyl]acetamide (AZD-5423)
van Kampen RJ
Effects of ticlopidine on pharmacokinetics of losartan and its main metabolite EXP3174 in rats
InChiKey: JAMULYFATHSZJM-UHFFFAOYSA-N
AZD6244 (Selumetinib) - MEK Inhibitor. CAS# 606143-52-6 0192 Formula: C17H18N6AZD6244, CAS No. 606143 52 6, (Selumetinib, ARRY 142886) is an orally active, highly potent and selective non ATP competitive MEK inhibitor, inhibiting MEK1 with an IC50 of 14 nM. In vitro cell viability inhibition screening of a tumor cell line panel found that cell lines harboring BRAF or RAS mutations were more likely to be sensitive to AZD6244. Treatment of primary HCC cells with AZD6244 led to growth inhibition, caspase 3 and caspase 7