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FMK 10763 Fosaprepitant is a weak inhibitor

SKU: 59742102186

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Description

Fosaprepitant is a weak inhibitor of CYP3A4

The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle and the integrity of the epidermal barrier

It binds to the enzyme active site and inhibits DNMT enzymatic activity with an IC50 ~ 115 nM

CAS Number: 371935-74-9

Pennypacker BL

FMK 10763 Fosaprepitant is a weak inhibitorFmk is an irreversible ribosomal S6 kinase inhibitor 1 2 inhibitor. Product information CAS Number: 821794 92 7 Molecular Weight: 342. 37 Formula: C18H19FN4O2 Chemical Name: 1 [4 amino 7 (3 hydroxypropyl) 5 (4 methylphenyl) 7H pyrrolo[2,3 d]pyrimidin 6 yl] 2 fluoroethan 1 one Smiles: CC1C=CC(=CC=1)C1C2=C(N)N=CN=C2N(CCCO)C=1C(=O)CF InChiKey: IKLGYJACVCXYIL UHFFFAOYSA N InChi: InChI=1S C18H19FN4O2 c1 11 3 5 12(6 4 11)14 15 17(20)21 10 22 18(15)23(7 2 8

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