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15(9):1184-8
2012 Jun 10
Smiles: CN1CCN(CC2C=CC(=CC=2)C(=O)NC2=CC(NC3=NC(=CC=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
(2004) J Med Chem
InChiKey: JWYIGNODXSRKGP-UHFFFAOYSA-N
L-779450 Catalog No.:M8298-10 15(9):1184-8L 779450 is a potent, selective and ATP competitive Raf kinase inhibitor (IC50 = 10 nM). L 779450 suppresses DNA synthesis and induces apoptosis in cells that proliferate in response to Raf 1 and A Raf but not B Raf. Product information CAS Number: 303727 31 3 Molecular Weight: 347. 80 Formula: C20H14ClN3O Chemical Name: 2 chloro 5 [2 phenyl 5 (pyridin 4 yl) 1H imidazol 4 yl]phenol Smiles: OC1=CC(=CC=C1Cl)C1N=C(NC=1C1C=CN=CC=1)C1C=CC=CC=1 InChiKey:
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