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A839977 is a P2X7R antagonist
CAS Number: 862974-25-2
57Dihydroxyflavone
Molecular Weight: 286
3-[(2-methylphenyl)methylsulfanyl]-6-pyridin-2-ylpyridazine
Cinobufotalin Catalog No.:M8397-10 A839977 is a P2X7R antagonistCinobufotalin is a steroid glycoside that reduces SRC 3 protein levels in MCF 7 breast cancer cells, Na+ K+ pump activity, viability, and cell attachment of C7 MDCK cells, and expression of the epithelial mesenchymal (EMT) markers E cadherin, vimentin, ZEB1, and Slug in. Cinobufotalin is cytotoxic to A549, H460, and HTB 58 lung cancer cells. In vivo, Cinobufotalin reduces tumor volume and increases survival in an A549 mouse xenograft model. Product
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