AT 1015 47117096 hydrochloride InChi: InChI=1S/C53H77N15O13S2/c1-7-28(4)44(53(80)81)68-52(79)37(16-27(2)3)63-51(78)41(21-43(70)71)67-47(74)36(13-15-83-6)62-50(77)40(20-42(55)69)66-49(76)39(19-31-24-57-26-60-31)65-48(75)38(18-30-23-56-25-59-30)64-46(73)35(12-14-82-5)61-45(72)33(54)17-29-22-58-34-11-9-8-10-32(29)34/h8-11

InChi: InChI=1S/C53H77N15O13S2/c1-7-28(4)44(53(80)81)68-52(79)37(16-27(2)3)63-51(78)41(21-43(70)71)67-47(74)36(13-15-83-6)62-50(77)40(20-42(55)69)66-49(76)39(19-31-24-57-26-60-31)65-48(75)38(18-30-23-56-25-59-30)64-46(73)35(12-14-82-5)61-45(72)33(54)17-29-22-58-34-11-9-8-10-32(29)34/h8-11

H2O : 5 mg/mL (48

is a selective and reversible inhibitor of IκB kinase 2 (IKK2) that may target osteoclastogenesis

Chemical Name: N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-[(1Z)-1-({[(3R)-morpholin-3-yl]methoxy}imino)but-2-yn-1-yl]quinazolin-4-amine

4-dihydroxyoxolan-2-yl]methyl sulfamate

AT 1015 47117096 hydrochloride InChi: InChI=1S/C53H77N15O13S2/c1-7-28(4)44(53(80)81)68-52(79)37(16-27(2)3)63-51(78)41(21-43(70)71)67-47(74)36(13-15-83-6)62-50(77)40(20-42(55)69)66-49(76)39(19-31-24-57-26-60-31)65-48(75)38(18-30-23-56-25-59-30)64-46(73)35(12-14-82-5)61-45(72)33(54)17-29-22-58-34-11-9-8-10-32(29)34/h8-11AT 1015 is a potent antagonist of 5 HT2A receptor . The 5 HT2A receptor is a G protein coupled receptor and a subtype of the 5 HT2 receptor, which belongs to the serotonin receptor family. The 5 HT2A receptor plays an important role in clathrin mediated endocytosis of JC virus, the human polyoma virus which causes progressive multifocal leukoencephalopathy (PML). AT 1015 is a potent 5 HT2A receptor antagonist. AT 1015 bound to 5 HT2 receptors in