Tenovin 6 Hydrochloride Catalog No.:M9044-10 and blocks Wnt signaling in

and blocks Wnt signaling in C57BL/6 mice

BAY2416964 specifically binds to AhR

Smiles: CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@H]1C2=CC=CC=C2CCN(C)C1=O

MM-102 specifically reduces expression of two critical MLL1 target genes (HoxA9 and Meis-1)

N[C@@H](CC1=CC(=CC(CP(O)(O)=O)=C1)C1=CC=CC=C1Cl)C(O)=O

Tenovin 6 Hydrochloride Catalog No.:M9044-10 and blocks Wnt signaling inTenovin 6, also known as Tnv 6, is a bioactive small molecule SIRT2 inhibitor with anti neoplastic activity. Inhibition of the Sirtuin class of protein deacetylases with activation of p53 function is associated with the pro apoptotic effects of Tnv 6 in many tumors. Tnv 6 causes non genotoxic cytotoxicity, without adversely affecting human clonogenic hematopoietic progenitors in vitro, or murine hematopoiesis. Mechanistically, exposure of CLL cells to