Sertraline Hydrochloride IN-1 More recent research in animal

More recent research in animal models suggests that isradipine may have potential uses for treating Parkinson's disease

8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1

Formula: C7H10N2OS

InChi: InChI=1S/C17H15NO3/c19-15-11-16(18-7-9-20-10-8-18)21-17-13-4-2-1-3-12(13)5-6-14(15)17/h1-6

blocking phosphorylation of Y397 with an IC50 value of about 1 μM

Sertraline Hydrochloride IN-1 More recent research in animalSertraline, also known as , is a selective serotonin uptake inhibitor that is used in the treatment of depression. Sertraline is primarily a serotonin reuptake inhibitor (SRI) with a binding affinity towards the serotonin transporter of Ki=2. 8 nM or in that range. Sertraline is also a dopamine reuptake inhibitor, (<50 nmol L). However, this is not considered a tight binding, and this action is only 10% of its potency as a monoamine reuptake