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1262036-50-9
BUQ57 was dosed to mice bearing human lung cancer cell line H2122 xenografts by intraperitoneal injection at 50 mg/Kg once per day
It binds in the WDR5 peptide-binding pocket and inhibits the catalytic activity of the MLL core complex in vitro
(2009) PLoS One
PRMT1 Upregulated by Epithelial Proinflammatory Cytokines Participates in COX2 Expression in Fibroblasts and Chronic Antigen-Induced Pulmonary Inflammation
TA 02 - CAS# 1784751-19-4 Catalog No.:M6704-10 1262036-50-9TA 02, CAS No. 1784751 19 4, is a p38 MAPK inhibitor with IC50 of 20 nM. Product information CAS Number: 1784751 19 4 Molecular Weight: 333. 33 Formula: C20H13F2N3 Synonym: TA 02 TA 02 TA02 Chemical Name: 4 (2 (2 fluorophenyl) 4 (4 fluorophenyl) 1H imidazol 5 yl)pyridine Smiles: FC1C=CC(=CC=1)C1N=C(NC=1C1C=CN=CC=1)C1=CC=CC=C1F InChiKey: QIFJOFNVIVQRNJ UHFFFAOYSA N InChi: InChI=1S C20H13F2N3 c21 15 7 5 13(6 8 15)18 19(14 9 11 23 12 10 14)25 20(24 18)16