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2 hours) inhibits chromatin binding of CECR2 BRD within SW48 cells
and is not toxic to nontumorigenic cells
23(4):567-577
Smiles: CC1(C)[C@@H]2CC[C@]3(C)[C@H](CC[C@@H]4[C@H]5[C@@H](CC[C@]5(C)CC[C@@]34C)C(C)=C)[C@@]2(C)CCC1=O
Gusacitinib (ASN-002) shows a favorable safety profile in rat and dog toxicology studies
Sulfo-SPDP-C6-NHS sodium 1329 2 hours) inhibits chromatin bindingSulfo SPDP C6 NHS sodium is a cleavable ADC linker used in the synthesis of antibody drug conjugates (ADCs). Product information CAS Number: 169751 10 4 Molecular Weight: 527. 57 Formula: C18H22N3NaO8S3 Chemical Name: sodium 2,5 dioxo 1 ({6 [3 (pyridin 2 yldisulfanyl)propanamido]hexanoyl}oxy)pyrrolidine 3 sulfonate Smiles: [Na+].[O ]S(=O)(=O)C1CC(=O)N(OC(=O)CCCCCNC(=O)CCSSC2=CC=CC=N2)C1=O InChiKey: ZAPNXDUFCQIHFS UHFFFAOYSA M InChi: InChI=1S