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Van Diest PJ
InChiKey: ABSXPNGWJFAPRT-UHFFFAOYSA-N
H2O/c1-2-13-3-5-14(6-4-13)9-15-7-8-16-12-27-22(17(16)10-15)21(26)20(25)19(24)18(11-23)28-22
Smiles: CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@@]21C
Molecular Weight: 1151
PRT062607 Hydrochloride hydrofolate Van Diest PJPRT062607, also known as P505 15, PRT2607, PRT62607, and BIIB057, is a novel, highly selective, and orally bioavailable small molecule SYK inhibitor (SYK IC(50) = 1 nM) with anti SYK activity that is at least 80 fold greater than its affinity for other kinases. P505 15 successfully inhibited SYK mediated B cell receptor signaling and decreased cell viability in NHL and CLL. Product information CAS Number: 1370261 97 4 Molecular Weight: 429. 91
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