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DDR1-IN-1 inhibits DDR2-mediated MT1-MMP activation in human rheumatoid synovial fibroblasts (RASF) upon collagen stimulation (IC50 < 2
Formula: C29H29Cl2N5O
Smiles: CCCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)C1=CC=C2OCCOC2=C1
CC1(CCCCCCC1)N1CCC(CC1)N1C(=NC2=CC=CC=C12)[C@H]1CNCCC1
Smiles: C[C@@H]1CCC2=NC=CC=C2C(=O)OC[C@@]2(C)O[C@@]34[C@@H](OC(C)=O)[C@@H]2[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@]3(COC(C)=O)[C@H](OC(C)=O)[C@H](OC(=O)C2C=CC=CC=2)[C@@H](OC1=O)[C@@]4(C)O
DC661 anodiene DDR1-IN-1 inhibits DDR2-mediated MT1-MMP activationDC661 is capable of deacidifying the lysosome and inhibiting autophagy significantly better than hydroxychloroquine (HCQ). DC661 induces apoptosis. Product information CAS Number: 1872387 43 3 Molecular Weight: 552. 58 Formula: C31H39Cl2N5 Chemical Name: 7 chloro N [6 ({6 [(7 chloroquinolin 4 yl)amino]hexyl}(methyl)amino)hexyl]quinolin 4 amine Smiles: CN(CCCCCCNC1C=CN=C2C=C(Cl)C=CC=12)CCCCCCNC1C=CN=C2C=C(Cl)C=CC=12 InChiKey: VJKCWFZTSDXOBS UHFFFAOYSA
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