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LP-922761 Size:Contact [email protected] for quotation 1-2H3/t20-/m1/s1

SKU: 65265662510

4.3
USD100.00 USD150.00

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Description

1-2H3/t20-/m1/s1

InChiKey: OISHBINQIFNIPV-JOCHJYFZSA-N

Thrombin Receptor Activator Peptide 6

NC1NC(=O)C2N=CN([C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C=2N=1

ITC experiments have confirmed the strong binding of CU-CPT9b with a Kd of 21 nM

LP-922761 Size:Contact [email protected] for quotation 1-2H3/t20-/m1/s1LP 922761 is a potent, selective and orally active adapter protein 2 associated kinase 1 (AAK1) inhibitor with IC50s of 4. 8 nM and 7. 6 nM in enzyme and cell assays, respectively. LP 922761 also inhibits BMP 2 inducible protein kinase (BIKE) with an IC50 of 24 nM. LP 922761 exhibits no significant activity at cyclin G associated kinase (GAK), opioid, adrenergic 2 or GABAa receptors. Product information CAS Number: 1454808 95 7 Molecular Weight: 410.

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