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PluriSIn-1 was identified by a high-throughput screening against undifferentiated human ESCs
pp 850–855
19542-67-7
3(11):2099-106
3-triazol-1-yl)benzyl)-2-(2-isopropylphenyl)-5-methylpyrimidin-4-amine
I-BRD9 - Bromodomain Containing Protein 9 (BRD9) Inhibitor. CAS# 1714146-59-4 156 PluriSIn-1 was identified by aI BRD9, CAS No. 1714146 59 4, is a potent, selective and cell permeable Bromodomain Containing Protein 9 (BRD9) inhibitor with Kd ~1. 9 nM. It has >700 fold selectivity over the BET family and 200 fold over the highly homologous bromodomain containing protein 7 (BRD7). It downregulates CLEC1, DUSP6, FES and SAMSN1 genes in Kasumi 1 cells. I BRD9 is the first selective tool compound available to elucidate the cellular phenotype of BRD9 bromodomain
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