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KL001 was used at 10-50 µM in vitro and in cellular assays
Smiles: O=C1NC(=O)C(=C1C1=CNC2=CC=CC=C21)C1=CNC2=CC=CC=C21
Smiles: COC1=CC=C(C=C1OC1CCCC1)[C@H]1CC(=O)NC1
Dyatkina N
InChi: InChI=1S/C26H34ClN6O2P/c1-32(2)18-12-14-33(15-13-18)19-10-11-21(23(16-19)35-3)30-26-28-17-20(27)25(31-26)29-22-8-6-7-9-24(22)36(4
YAP-TEAD-IN-1 TFA 64 Racemate KL001 was used at 10-50YAP TEAD IN 1 TFA is a potent and competitive peptide inhibitor of YAP TEAD interaction (IC50=25 nM). YAP TEAD IN 1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50 171) (Kd= 40 nM). Product information CAS Number: 1659305 79 9 Molecular Weight: 2133. 89 Formula: C95H145ClF3N23O23S2 Chemical Name: (4S) 4 ((2S) 1 ((2S) 1 ((2S) 2 ((3S, 6S, 9S, 18S, 21S, 24S, 27S, 30S, 35aS) 18 ((S) 2 ((S) 1 ((S) 2 acetamido
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