brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics
Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris
Epidermal growth factor receptor blockade with C225 modulates proliferation
Exposure of the COLO205 cells to Cucurbitacin I significantly decreases cell viability
and nuclear factor-κB-p65 by 10
SF2523 Catalog No.:M18719-C brain-penetrant and orally active chaperone-mediatedSF2523 is a highly selective and potent inhibitor of PI3K with IC50s of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3K, PI3K, DNA PK, BRD4 and mTOR, respectively. Product information CAS Number: 1174428 47 7 Molecular Weight: 371. 41 Formula: C19H17NO5S Chemical Name: 3 (2,3 dihydro 1,4 benzodioxin 6 yl) 5 (morpholin 4 yl) 7H thieno[3,2 b]pyran 7 one Smiles: O=C1C=C(OC2=C1SC=C2C1C=C2OCCOC2=CC=1)N1CCOCC1 InChiKey: BYTKNUOMWLJVNQ UHFFFAOYSA N InChi: