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is a highly selective inhibitor of MEK1/2 with IC50 of 0
Smiles: CC1OC(=O)OC=1CN1CCN(CC1)C1=CC2=C(C=C1F)C(=O)C(=C1SC(C)N21)C(O)=O
it is the muscle present in places such as the gut and uterus
6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-{[(3S
2-oxazol-3-yl)carbamoyl]amino}phenyl)-5-[(1-ethyl-2
BMS-754807 - CAS# 1001350-96-4 cone is a highly selective inhibitorBMS 754807 is an orally bioavailable antagonist of human insulin like growth factor type I receptor (IGF 1R) with potential antineoplastic activity. IGF 1R antagonist BMS 7548077 binds to IGF 1R, preventing IGF 1 ligand binding and activation of IGF 1R mediated signaling pathways; inhibition of IGF 1R mediated signaling pathways may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF 1R is a receptor
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