RAS inhibitor Abd-7 Size:Contact [email protected] for quotation PR-619 was used at 10-50

PR-619 was used at 10-50 µM final concentration in various in vitro assays

Chemical Name: 1-(4-(4-(8-oxa-3-azabicyclo[3

5-dihydroxybenzene-1-sulfonate)

It retains the activity of later-generation cephalosporins having broad-spectrum activity against Gram-negative bacteria

with IC50 of 26±3 nM (n=21)

RAS inhibitor Abd-7 Size:Contact [email protected] for quotation PR-619 was used at 10-50RAS inhibitor Abd 7, a potent RAS binding compound (Kd=51 nM), is a RAS effector protein protein interaction (PPI) inhibitor. RAS inhibitor Abd 7 interacts with RAS inside the cells, prevents RAS effector interactions and inhibits endogenous RAS dependent signaling. RAS inhibitor Abd 7 impairs the PPI of various mutant KRAS proteins with PI3K, CRAF and RALGDS as well as NRAS Q61H and HRAS G12V. Product information CAS Number: 2351843 48 4 Molecular