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N-Arachidonylglycine Catalog No.:M18819-C Smiles: CC(=O)O[C@]12C[C@H](OC)[C@@]3(O)C[C@H]([C@@H]1[C@H]3OC(=O)C1=CC=C(C=C1)OC)C13[C@@H]4[C@@H](OC)C2C1N(C[C@@]4(CC[C@@H]3OC)COC)CC

SKU: 68242229623

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Description

Smiles: CC(=O)O[C@]12C[C@H](OC)[C@@]3(O)C[C@H]([C@@H]1[C@H]3OC(=O)C1=CC=C(C=C1)OC)C13[C@@H]4[C@@H](OC)C2C1N(C[C@@]4(CC[C@@H]3OC)COC)CC

12'-tetrahydrogenio-5

assessed as either a reduction in fluorescence of the voltage-sensitive dye bis-(1

is shown to be an even more potent and selective inhibitor of GRK2 with an IC50 of 0

InChiKey: AOORBROPMMRREB-HBPAQXCTSA-N

N-Arachidonylglycine Catalog No.:M18819-C Smiles: CC(=O)O[C@]12C[C@H](OC)[C@@]3(O)C[C@H]([C@@H]1[C@H]3OC(=O)C1=CC=C(C=C1)OC)C13[C@@H]4[C@@H](OC)C2C1N(C[C@@]4(CC[C@@H]3OC)COC)CCN Arachidonylglycine (NA Gly), a carboxylic analog of the endocannabinoid anandamide (AEA), is a GPR18 agonist (EC50 = 44. 5 nM). Unlike AEA, N Arachidonylglycine has no activity at either CB1 or CB2 receptors. N Arachidonylglycine inhibits GLYT2 (IC50 = 5. 1 M). N Arachidonylglycine also is an effective activator of endometrial cell migration. Product information CAS Number: 179113 91 8 Molecular Weight: 361. 52 Formula: C22H35NO3 Chemical Name: 2

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