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Ro 64-6198 is at least 100 times more selective for the NOP receptor over the classic opioid receptors
GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM)
SB-242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases such as autoimmune or inflammatory diseases
47mg/kg on adjuvant-induced arthritis and collagen-induced arthritis
or nearly as effectively
PF-04937319 3002 Ro 64-6198 is at leastPF 04937319 is a glucokinase activator (GKA) with EC50 value of 154. 4 M, one of the most promising strategies for the treatment of type 2 diabetes mellitus. PF 04937319 is designed to maintain glucose lowering efficacy while mitigating the risk of hypoglycaemia observed with many other GKAs. Product information CAS Number: 1245603 92 2 Molecular Weight: 432. 43 Formula: C22H20N6O4 Chemical Name: N,N dimethyl 5 ({2 methyl 6 [(5 methylpyrazin 2