ALK2-IN-2 - CAS# 2254409-25-9 size:10mg solid 118(3):749-55

118(3):749-55

It binds to HCV nonstructural 3 NS3 (HCV) active site

1021/tx200525n

SAM486A treatment resulted in the rapid accumulation of proapoptotic proteins p53 and Mdm2

p300 and CBP are transcriptional co-activators that modulate DNA replication

ALK2-IN-2 - CAS# 2254409-25-9 size:10mg solid 118(3):749-55ALK2 IN 2, CAS No. 2254409 25 9, is a potent and selective inhibitor of activin receptor like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700 fold selectivity against ALK3. Product information CAS Number: 2254409 25 9 Molecular Weight: 497. 61 Formula: C28H27N5O2S Chemical Name: ALK2 IN 2 Smiles: CC(C1C=CC(=CC=1)C1=CN2N=CC(=C2N=C1)C1=CC=C(C2=CC=CC=C21)S(N)(=O)=O)N1CCCC1 InChiKey: IPESYYFOXATSFJ UHFFFAOYSA N InChi: InChI=1S C28H27N5O2S c1 19(32 14 4