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Dual PARP EGFR ligand for PROTAC Catalog No.:M17144-C Navelbine base

SKU: 70165967152

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Description

Navelbine base

AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator

InChi: InChI=1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H

resulting in abnormal N protein oligomerization that was further confirmed in the cell

Chemical Name: (2E)-N-(2-aminophenyl)-3-{1-[4-(1-methyl-1H-pyrazol-4-yl)benzenesulfonyl]-1H-pyrrol-3-yl}prop-2-enamide

Dual PARP EGFR ligand for PROTAC Catalog No.:M17144-C Navelbine baseDual PARP EGFR ligand for PROTAC incorporates a ligand for PARP and EGFR , and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). Dual PARP EGFR ligand for PROTAC can be used in the synthesis of DP C 4, which is CRBN based dual PROTAC for simultaneous degradation of EGFR and PARP. Product information Molecular Weight: 1020. 52 Formula: C53H56ClF2N9O8 Chemical Name: 6 ((4 ((3 chloro 4 fluorophenyl)amino) 7 methoxyquinazolin 6

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