Rho-Kinase-IN-1 - CAS# 1035094-83-7 227 SKL2001 (40 μM) enhances round-shape

SKL2001 (40 μM) enhances round-shape spheroid formation and E-cadherin expression

JK184 was suggested to use at 1-5 µM concentration in vitro and in the cellular assays

de Oliveira AC

2014 Nov 17

Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor

Rho-Kinase-IN-1 - CAS# 1035094-83-7 227 SKL2001 (40 μM) enhances round-shapeRho Kinase IN 1, CAS No. 1035094 83 7, is a Rho kinase (ROCK) inhibitor (Ki values of 30. 5 and 3. 9 nM for ROCK1 and ROCK2, respectively) extracted from US20090325960A1, compound 1. 008. Product information CAS Number: 1035094 83 7 Molecular Weight: 352. 50 Formula: C20H24N4S Chemical Name: Rho Kinase IN 1 Smiles: CSC1=CC=C(CN2CC(CCC2)NC2C=C3C=NNC3=CC=2)C=C1 InChiKey: DPZSYTMLVCLGRU UHFFFAOYSA N InChi: InChI=1S C20H24N4S c1 25 19 7 4 15(5 8 19)13 24