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TPMPA antagonizes the GABA currents of ρ1 receptors (IC50 = 1
promotes oligodendrocyte precursor cell (OPC) differentiation in a dose-dependent manner
In competitive experiments using membranes prepared from Chinese hamster ovary cells expressing the bradykinin receptor subtypes
Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats
Solubility: DMSO : ≥ 32 mg/mL (88
NB-360 Size:Contact [email protected] for quotation TPMPA antagonizes the GABA currentsNB 360 is a potent, brain penetrable, and orally bioavailable dual BACE1 BACE2 inhibitor (IC50: mouse and human BACE1=5 nM; BACE2=6 nM). NB 360 shows a superior pharmacological profile and robust reduction of amyloid and neuroinflammation in amyloid precursor protein(APP) transgenic mice. NB 360 can completely block the progression of A deposition in the brains of APP transgenic mice. NB 360 shows excellent selectivity over the related aspartyl
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