ARRY-520 - CAS# 885060-09-3 azone Maleate BG45 was used at 10

BG45 was used at 10 µM final concentration in various in vitro assays

Functional assays

Ro 32-0432

Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases

The transcriptional changes elicited by THAL-SNS-032 are more like those caused by NVP-2 than those induced by SNS-032

ARRY-520 - CAS# 885060-09-3 azone Maleate BG45 was used at 10Filanesib, also known as ARRY 520, is a synthetic, small molecule targeting the kinesin spindle protein (KSP) with potential antineoplastic activity. KSP inhibitor ARRY 520 specifically inhibits KSP (kinesin 5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. Because KSP is not involved in postmitotic