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one of 3-Oxoisoindoline-1-carboxamides
Smiles: CC1=CC(/N=N/C2C=CC(=CC=2)S(=O)(=O)NC2=CC=CC=N2)=C(N)C=C1O
myristoylated (10 μM) blocks PKMζ-mediated AMPA receptor (AMPAR) potentiation
and leukemia) is observed with IC50 values of 0
Exhibits no detectable binding of VHL
(Rac)-BRD0705 - CAS# 1597440-03-3 Size:Contact [email protected] for quotation one of 3-Oxoisoindoline-1-carboxamides(Rac) BRD0705 is a less active racemate of BRD0705. BRD0705 is a potent, paralog selective and orally active GSK3 inhibitor with an IC50 of 66 nM and a Kd of 4. 8 M. BRD0705 displays increased selectivity for GSK3 (8 fold) versus GSK3 (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML). Product information CAS Number: 1597440 03 3 Molecular Weight: 321. 42 Formula: C20H23N3O Chemical Name: 4 ethyl 7,7 dimethyl 4 phenyl
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