![Varenicline Hydrochloride Catalog No.:M10977-10 Smiles: COC1=CC=C(C=C1CO)C1=CC=C2C(N=C(N=C2N2CCOC[C@@H]2C)N2CCOC[C@@H]2C)=N1](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M10977_1621562785.gif?v=1621562787)
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Smiles: COC1=CC=C(C=C1CO)C1=CC=C2C(N=C(N=C2N2CCOC[C@@H]2C)N2CCOC[C@@H]2C)=N1
selective and orally available dual inhibitor of pan-PI3-kinase and mTOR with IC50 of 3
PC-3 prostate cancer
Neuroscience
Chemical Name: 1-(2-{[3-(2-phenylethynyl)pyrido[2
Varenicline Hydrochloride Catalog No.:M10977-10 Smiles: COC1=CC=C(C=C1CO)C1=CC=C2C(N=C(N=C2N2CCOC[C@@H]2C)N2CCOC[C@@H]2C)=N1Varenicline is a nicotinic receptor partial agonistit stimulates nicotine receptors more weakly than nicotine itself does. In this respect it is similar to cytisine and different from the nicotinic antagonist, bupropion, and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. Varenicline displays full agonism on 7 nicotinic acetylcholine receptors and is a partial agonist on the 42, 34, and 62 subtypes. In addition, it is a
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