Nepicastat Size:Solid 10 mg Smiles: CC1=C(C2C=CC(O)=CC=2)N(CC2C=CC(=CC=2)OCCN2CCCCCC2)C2=CC=C(O)C=C21

Smiles: CC1=C(C2C=CC(O)=CC=2)N(CC2C=CC(=CC=2)OCCN2CCCCCC2)C2=CC=C(O)C=C21

3-dihydroxypropyl phosphonato]oxy}ethyl)trimethylazanium

Acipimox treatment resulted in a robust elevation in expression of nuclear-encoded mitochondrial gene sets and a mitonuclear protein imbalance

3-weekly i

In a UT7/EPO cell line

Nepicastat Size:Solid 10 mg Smiles: CC1=C(C2C=CC(O)=CC=2)N(CC2C=CC(=CC=2)OCCN2CCCCCC2)C2=CC=C(O)C=C21Nepicastat, also known as SYN117 and RS 25560 197, is an inhibitor of dopamine beta hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. It has been studied as a possible treatment for congestive heart failure, and appears to be well tolerated. As of 2012, clinical trials to assess nepicastat as a treatment for post traumatic stress disorder (PTSD) and cocaine dependence have been completed. In Phase 2 study treatment