Itraconazole-d5 oxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside falciparum with IC50s of 1

falciparum with IC50s of 1

InChiKey: VMQKWKNTSXIWGW-UHFFFAOYSA-N

Smiles: FC1=C2NC(CNC3=NC(=NC4=C(C=NN34)C3CC3)N3CCNCC3)=NC2=CC=C1F

CAS Number: 150281-21-3

CAS Number: 202471-84-9

Itraconazole-d5 oxy-3-prenylnaphthalene-1-O-β-D-glucopyranoside falciparum with IC50s of 1Itraconazole d5 (R51211 d5) is the deuterium labeled Itraconazole. Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC50 of ~800 nM. Itraconazole potently inhibits lanosterol 14 demethylase (cytochrome P450 enzyme), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Product information CAS