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Selective Seviteronel (VT-464) CYP17 lyase inhibition is as effective as AA CYP17 inhibition in this model
The inhibitory effect of the lowest concentration (5 nM) of JYL 1421 reaches the level of significance and 1 μM almost abolishes the response
1 mg/kg (n=16) Zatosetron maleate
InChi: InChI=1S/C19H18F3N5OS/c1-12-23-26-18(29-12)15-6-7-17(25-24-15)27-10-8-13(9-11-27)28-16-5-3-2-4-14(16)19(20
Formula: C20H25N6O8P
Ro 04-5595 hydrochloride n dimyristate Selective Seviteronel (VT-464) CYP17 lyaseProduct information CAS Number: 64047 73 0 Molecular Weight: 368. 30 Formula: C19H23Cl2NO2 Chemical Name: (1R,2S) 1 [2 (4 chlorophenyl)ethyl] 7 hydroxy 6 methoxy 2 methyl 1,2,3,4 tetrahydroisoquinolin 2 ium chloride Smiles: [Cl ]. COC1C=C2CC[N@H+](C)[C@H](CCC3C=CC(Cl)=CC=3)C2=CC=1O InChiKey: NVIPBLQAFKRFSZ UNTBIKODSA N InChi: InChI=1S C19H22ClNO2. ClH c1 21 10 9 14 11 19(23 2)18(22)12 16(14)17(21)8 5 13 3 6 15(20)7 4 13; h3 4,6 7,11 12,17,22H,5,8
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