SGC-iMLLT Catalog No.:M21694-C 3-benzodiazol-1-yl]pyrimidin-2-yl}amino)-4-methoxyphenyl)prop-2-enamide

3-benzodiazol-1-yl]pyrimidin-2-yl}amino)-4-methoxyphenyl)prop-2-enamide

OMO-1 (formerly JNJ-38877618)

28 mM) H2O : 2 mg/mL (9

2Na/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15

and 100 mg/kg dosage cohorts

SGC-iMLLT Catalog No.:M21694-C 3-benzodiazol-1-yl]pyrimidin-2-yl}amino)-4-methoxyphenyl)prop-2-enamideSGC iMLLT is a first in class chemical probe and a potent, selective inhibitor of MLLT1 3 histone interactions with an IC50 of 0. 26 M. SGC iMLLT shows high binding activity towards MLLT1 YEATS domain (YD) and MLLT3 YD (AF9 YEATS3) with Kds of 0. 129 and 0. 077 M, respectively. Product information CAS Number: 2255338 25 9 Molecular Weight: 388. 47 Formula: C22H24N6O Chemical Name: 1 methyl N (2 {[(2S) 2 methylpyrrolidin 1 yl]methyl} 1H 1,3 benzodiazol