4-Methylhistamine dihydrochloride Catalog No.:M22257-C a pure toxic substance isolated

a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like

Loriaux MM

Smiles: CN([C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)O[Na])OC)[C@@H](C)CC)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C

treated for 14 consecutive days) reduces leukemia burden in mice

CAS Number: 1046045-61-7

4-Methylhistamine dihydrochloride Catalog No.:M22257-C a pure toxic substance isolated4 Methylhistamine dihydrochloride (or 4 methylhistamine) is a selective agonist of H4 receptor with a pEC50 value of 7. 40. 1 (=1) . In the chemotaxis of mast cells and leukocytes to sites of inflammation, the histamine H4 receptor (H4R) is involved . In transfected cells, 4 methylhistamine bound to hH4R with the highest affinity, compared to the binding to other histamine receptors. The interaction between 4 methylhistamine and hH4R showed a higher