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L-Leucyl-L-Leucine methyl ester (10-250 μM
CTEP allows the exploration of the full therapeutic potential of mGlu5 inhibitors for indications requiring chronic receptor inhibition
InChi: InChI=1S/C23H26N2O2
8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1
and 50 nM for the human CA isoforms CAI
Aβ42-IN-1 free base 13437 L-Leucyl-L-Leucine methyl ester (10-250 μMA42 IN 1 free base (compound 1v) is an orally active, high brain exposure secretase modulator. A42 IN 1 free base potently reduces A42 levels with an IC50 value of 0. 091 M, and significantly reduces brain A42 levels in mice. A42 IN 1 free base is a promising compound for the treatment of Alzheimers disease. Product information CAS Number: 2434633 17 5 Molecular Weight: 462. 54 Formula: C29H26N4O2 Chemical Name: 5 [8 ({[1,1' biphenyl] 4 yl}methoxy) 2
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