Pay in 4 interest-free payments of $34.75 Learn more
Ships within 48 hours · Estimated delivery Aug 13 - Aug 18
Spanjersberg R
Smiles: O=C(NCCS(=O)(=O)C1=CC=C(C=N1)C(F)(F)F)C1C=CC(Cl)=CC=1
Molecular Weight: 266
(2011) Journal of the American Chemical Society
Formula: C20H17F2N3O2
SD70 - Histone Demethylase JMJD2 Inhibitor. CAS# 332173-89-4 size:2 mg solid Spanjersberg RSD70, CAS No. 332173 89 4, is a potent, selective and cell permeable inhibitor of histone demethylase JMJD2 (KDM4C), identified by phenotypic screening for inhibitors of ligand and genotoxic stress induced translocations in prostate cancer cells. Through Chem seq approach, SD70 was found to inhibit the androgen dependent AR program and prostate cancer cell growth, acting, at least in part, by functionally inhibiting the Jumonji domain containing