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InChi: InChI=1S/C17H19ClN2S
6R)-6-(azepan-1-ylmethylideneamino)-3
Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity
FG-2216 (40-60 mg/kg
Cravatt BF
PD-089828 camsule.2Na InChi: InChI=1S/C17H19ClN2SPD 089828 is an ATP competitive inhibitor of FGFR 1, PDGFR and EGFR (IC50s=0. 15, 1. 76, and 5. 47 M, respectively) and a noncompetitive inhibitor of c Src tyrosine kinase (IC50=0. 18 M). PD 089828 also inhibits MAPK with an IC50 of 7. 1 M. PD 089828 inhibits PDGF , EGF and bFGF mediated tyrosine kinase receptor autophosphorylation in vitro. PD 089828 has a long lasting cellular activity. Product information CAS Number: 179343 17 0 Molecular Weight:
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