![EGFR-IN-1 hydrochloride Catalog No.:M27662-C 3-hexafluoropropan-2-yl 4-[(3-phenoxyphenyl)methyl]piperazine-1-carboxylate](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M27662_1636001370.gif?v=1636001372)
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3-hexafluoropropan-2-yl 4-[(3-phenoxyphenyl)methyl]piperazine-1-carboxylate
4-dibromo-2
It reacts with all four DNA bases but with different efficiency: G >C > A >T
InChi: InChI=1S/C13H22N6
Smiles: CCOC1=CC(N)=C(C=C1)OC1C=CC(=CC=1)OCC1=CC(F)=CC=C1F
EGFR-IN-1 hydrochloride Catalog No.:M27662-C 3-hexafluoropropan-2-yl 4-[(3-phenoxyphenyl)methyl]piperazine-1-carboxylateEGFR IN 1 hydrochloride is an orally active and irreversible L858R T790M mutant selective EGFR inhibitor. EGFR IN 1 hydrochloride potently inhibits Gefitinib resistant EGFR L858R, T790M with 100 fold selectivity over wild type EGFR. EGFR IN 1 hydrochloride displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity. Product information CAS Number: 2227455 78 7 Molecular Weight: 551. 04
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