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EPZ005687 is a potent inhibitor of EZH2 (K(i) of 24 nM)
whereas mitotic activity of OSC-1 cells remain unchanged
InChiKey: SMHKJRVPSDESLS-UHFFFAOYSA-N
Smiles: CC(C)(C)OC(=O)NC1C=CC(=CC=1)C(=O)NC1=CC2NC(=CC=2C=C1)C(=O)N1C[C@@H](CCl)C2C3=CC=CC=C3C(O)=CC1=2
DprE1-IN-4 exhibits acceptable pharmacokinetic property after p
BioE-1115 hyl anthranilate EPZ005687 is a potent inhibitorBioE 1115 is a highly selective and potent PAS kinase (PASK) inhibitor with an IC50 of ~4 nM. BioE 1115 is also a potent casein kinase 2 inhibitor with an IC50 of ~10 M. Product information CAS Number: 1268863 35 9 Molecular Weight: 339. 36 Formula: C19H18FN3O2 Chemical Name: 2 (4 fluorophenyl) 3 [methyl(propan 2 yl)amino]quinoxaline 6 carboxylic acid Smiles: CC(C)N(C)C1=NC2=CC(=CC=C2N=C1C1C=CC(F)=CC=1)C(O)=O InChiKey: JKKRYYTVQXUOKL UHFFFAOYSA N
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